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Effects of tricyclic antidepressants on muscarinic cholinergic receptor binding in mouse brain

✍ Scribed by Bryan Bohman; Angelos Halaris; Michael Karbowski

Book ID
118940095
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
505 KB
Volume
29
Category
Article
ISSN
0024-3205

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Binding affinities of four tricyclic ant
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✍ S. Batra; A. BiΓΆrklund πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 345 KB

The binding kinetics of tritiated quinuclidinyl benzilate (QNB) were studied in membrane preparations from human parotid and rabbit submandibular glands. Inhibition of 3H-QNB was then used to compare the anticholinergic activity of lofepramine, desipramine, imipramine and amitriptyline for muscarini