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Multistage carcinogenesis utilizing human genital cells and human papillomaviruses

✍ Scribed by Di Paolo, J.A.; Popescu, N.C.; Ablashi, D.V.; Lusso, P.; Zimonjic, D.B.; Woodworth, C.D.

Book ID
122351942
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
300 KB
Volume
72
Category
Article
ISSN
0378-4274

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## Abstract We consider the implications of multistage carcinogenesis for the incidence of cancer in human populations. When clonal expansion of partially altered cells is properly accounted for, we find it unnecessary to invoke genomic instability as an early event in malignant transformation. Env