Multistage carcinogenesis and the incide
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Suresh H. Moolgavkar; E. Georg Luebeck
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Article
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2003
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John Wiley and Sons
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English
β 72 KB
## Abstract We consider the implications of multistage carcinogenesis for the incidence of cancer in human populations. When clonal expansion of partially altered cells is properly accounted for, we find it unnecessary to invoke genomic instability as an early event in malignant transformation. Env