Multistage carcinogenesis and the fraction at risk
β Scribed by Stephan Morgenthaler; Pablo Herrero; William G. Thilly
- Book ID
- 105998356
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 167 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0303-6812
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Carcinogenesis is generally considered to be a multistage process classified under ''initiation,'' ''promotion,'' and ''progression,'' and it is therefore of interest to know how radiation might affect them. Models which are currently being used with some success to analyze a variety of data are bas
## Abstract We consider the implications of multistage carcinogenesis for the incidence of cancer in human populations. When clonal expansion of partially altered cells is properly accounted for, we find it unnecessary to invoke genomic instability as an early event in malignant transformation. Env