Multiplicity of mitochondrial inner membrane antigens from beef heart reacting with antimitochondrial antibodies in sera of patients with primary biliary cirrhosis
โ Scribed by H. Ishii; K. Saifuku; T. Namihisa
- Book ID
- 104176699
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 935 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0165-2478
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๐ SIMILAR VOLUMES
Antimitochondrial antibodies are characteristically detected in sera of patients with primary biliary cirrhosis. The antigens to which the antimitochondrial antibodies in primary biliary cirrhosis sera react have been located in the mitochondrial inner membrane. We have reported on four mitochondria
Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non