Antimitochondrial antibodies are characteristically detected in sera of patients with primary biliary cirrhosis. The antigens to which the antimitochondrial antibodies in primary biliary cirrhosis sera react have been located in the mitochondrial inner membrane. We have reported on four mitochondria
Isolation of tryptic fragment of antigen from mitochondrial inner membrane proteins reacting with antimitochondrial antibody in sera of patients with primary biliary cirrhosis
โ Scribed by Daisaku Muno; Eiki Kominami; Hideo Ishii; Koh Usui; Koji Saifuku; Yuji Sakakibara; Toshihiko Namihisa
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 814 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0270-9139
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๐ SIMILAR VOLUMES
Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non
Autoantibodies from rare patients with primary bili-gens. [1][2][3][4] Antibodies against the E2 subunits of the mitoary cirrhosis (PBC) recognize LBR, or lamin B receptor, chondrial oxo acid dehydrogenase complexes are found an integral membrane protein of the inner nuclear memin approximately 90%