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Multiple peptide synthesis using a single support (MPS3)

✍ Scribed by TJOENG, FOE S. ;TOWERY, DEREK S. ;BULOCK, JOSEPH W. ;WHIPPLE, DEBORAH E. ;FOK, KAM F. ;WILLIAMS, MARK H. ;ZUPEC, MARK E. ;ADAMS, STEVEN P.


Book ID
115099041
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
527 KB
Volume
35
Category
Article
ISSN
0367-8377

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Synthesis of peptide aldehydes on solid
✍ Marielle Paris; annie Heitz; Vincent Guerlavais; MichΓ¨le Cristau; Jean-Alain Feh πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 204 KB

A new strategy for the synthesis of peptide aldehydes on solid support is presented. Reaction of a N-protected or-amino aldehyde with MBHA-supported Wittig ou Winig-Horner reagent yielded resin-linked ~-~-unsaturated 8-amino derivative. After elongation of the peptide chain, ozonolysis produced fair