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Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions

✍ Scribed by Hahn, L. W.; Ritchie, M. D.; Moore, J. H.

Book ID
121871685
Publisher
Oxford University Press
Year
2003
Tongue
English
Weight
76 KB
Volume
19
Category
Article
ISSN
1367-4803

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Gene‐gene interaction plays an important role in the etiology of complex diseases, which may exist without a genetic main effect. Most current statistical approaches, however, focus on assessing an interaction effect in the presence of the gene's main effects. It would be very helpful to develop met