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Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction

✍ Scribed by Hongying Dai, Richard J Charnigo, Mara L Becker, J Steven Leeder…


Book ID
120698113
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
322 KB
Volume
6
Category
Article
ISSN
1756-0381

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## Abstract Gene‐gene interaction is believed to play an important role in understanding complex traits. Multifactor dimensionality reduction (MDR) was proposed by Ritchie et al. [2001. Am J Hum Genet 69:138–147] to identify multiple loci that simultaneously affect disease susceptibility. Although