## BACKGROUND. It has been observed that patients who have previously undergone radiotherapy have a lower rate of response to chemotherapy. ## METHODS. The authors investigated the effects of radiation on the expression of P-glycoprotein (Pgp), a multidrug-resistance gene product, in 56 patient
Multidrug resistance gene 1 expression in salivary gland adenocarcinomas and oral squamous-cell carcinomas
β Scribed by Takashi Uematsu; Takafumi Hasegawa; B. Yukihiro Hiraoka; Fuhito Komatsu; Takashi Matsuura; Aki-Sato Yamada; Minoru Yamaoka
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 564 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A high level of plasminogen activator inhibitorβ1 (PAIβ1 or __SERPINE1__) in tumor extracts is a marker of a poor prognosis in human cancers, including oral carcinomas. However, the mechanisms responsible for the upregulation of PAIβ1 in cancers remain unclear. Investigating specific PA
MRP has been identified as another multidrug-resistance (MDR) gene and may be involved in an alternative MDR mechanism in some solid tumors. We investigated the expres- sion of M R P mRNA in multidrug-resistant KB sublines (KB-8-5, KB-CZ, C -W and C A I to), human non-small-cell lung carcinomas (NSC
## Abstract ## Background. Defects in the mitotic spindle checkpoint have been proposed to contribute to the chromosomal instability observed in human cancers, including oral squamous cell carcinoma (OSCC). BUBR1 is a key component of the spindle checkpoint, whose role in oral carcinogenesis still
The MAGE, BAGE, and GAGE gene families code for distinct, tumor specific antigens that are recognized by cytotoxic T lymphocytes in the context of HLA molecules. The purpose of this study was to analyze MAGE, BAGE, and GAGE gene expression in the two major histologic types of esophageal carcinoma, s