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Multidrug resistance associated protein 2 mediates transport of prostaglandin E2

โœ Scribed by Dirk R. De Waart; Coen C. Paulusma; Cindy Kunne; Ronald P. J. Oude Elferink


Book ID
111237468
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
172 KB
Volume
26
Category
Article
ISSN
0106-9543

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The multidrug-resistance (MR) status of camptothecin (CPT) was investigated in colon adenocarcinoma HT29 cells, leukemia K562, and breast carcinoma MCF7 cells expressing P-glycoprotein (Pgp) and/or MR-associated protein (MRP1). The concentration that induced 50% growth inhibition (IC(50)) against CP