Effects of bosentan, an endothelin recep
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Yuji Mano; Takashi Usui; Hidetaka Kamimura
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Article
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2006
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John Wiley and Sons
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English
⚖ 111 KB
## Abstract The bile salt export pump (BSEP/Bsep/ABCB11) and multidrug resistance‐associated protein 2 (MRP2/Mrp2/ABCC2) are involved in bile acid‐dependent and ‐independent bile secretion, respectively. It has been reported that bosentan, an endothelin receptor antagonist, inhibits Bsep, which may