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Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump

✍ Scribed by Hidetaka Akita; Hiroshi Suzuki; Kousei Ito; Setsuo Kinoshita; Norihito Sato; Hajime Takikawa; Yuichi Sugiyama


Book ID
117047758
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
414 KB
Volume
1511
Category
Article
ISSN
0005-2736

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## Abstract The bile salt export pump (BSEP/Bsep/ABCB11) and multidrug resistance‐associated protein 2 (MRP2/Mrp2/ABCC2) are involved in bile acid‐dependent and ‐independent bile secretion, respectively. It has been reported that bosentan, an endothelin receptor antagonist, inhibits Bsep, which may