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Multicomponent Synthesis of 6 H -Dibenzo[ b,d ]pyran-6-ones and a Total Synthesis of Cannabinol

✍ Scribed by Nandaluru, Penchal Reddy; Bodwell, Graham J.


Book ID
118051001
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
801 KB
Volume
14
Category
Article
ISSN
1523-7060

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A one-pot synthesis of 8-amino-1-methoxy
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## Abstract 8-Amino-1-methoxy-6H-dibenzo[b,d]pyran-6-one was synthesized in a one-pot reaction of 2β€²,6β€²-dimethoxy-4-nitro-1,1β€²-biphenyl-2-carboxylic acid methyl ester using hydroiodic acid as a reagent to effect O-demethylation, lactonization, and nitro reduction to amine. This new reaction represe