## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folateβhomocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp
β¦ LIBER β¦
MTHFR (methylenetetrahydrofolate reductase) C677T polymorphism and psoriasis
β Scribed by Vladimir Vasku; Julie Bienertova-Vasku; Miroslav Necas; Anna Vasku
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 154 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0372-8722
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Spina bifida cystica (SB) is one of the most common and disabling of birth defects. Folic acid supplementation in mothers during the periconceptional period has been shown to prevent more than 70% of neural tube defects (NTD) including SB. However, the mechanism is unknown. We tested a series of mul