## Abstract Our previous results indicated a moderate association between the methylenetetrahydrofolate reductase (__MTHFR__) gene 677CβT variant and an increased risk of nonβsyndromic cleft lip with or without cleft palate (nsCL/P) among the northern but not southern population in China, suggestin
β¦ LIBER β¦
MTHFR is not a risk factor in the development of isolated nonsyndromic cleft lip and palate
β Scribed by Blanton, Susan H. ;Patel, Sketa ;Hecht, Jacqueline T. ;Mulliken, John B.
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 36 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0148-7299
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## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2
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