Mouse models of human diseases
β Scribed by Heiner Westphal
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 391 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
β¦ Synopsis
Cancer, poliomyelitis, Alzheimer's and Gaucher disease, a seemingly disparate array of disorders, have become the target of powerful genetic analysis and drug screening protocols, using mouse strains that have been genetically altered to serve as models for understanding the disease and for helping the patient.
π SIMILAR VOLUMES
## Abstract ## Background Geneβdirected enzyme prodrug therapy (GDEPT) based on the __E. coli__ enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically administered prodrug, fludar