Mouse models for extracellular matrix diseases
✍ Scribed by A. Aszódi; Alexander Pfeifer; Mikael Wendel; László Hiripi; Reinhard Fässler
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 222 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Cancer, poliomyelitis, Alzheimer's and Gaucher disease, a seemingly disparate array of disorders, have become the target of powerful genetic analysis and drug screening protocols, using mouse strains that have been genetically altered to serve as models for understanding the disease and for helping
To study the molecular mechanism for the development of B-cell dominant autoimmune diseases, several autoantibody transgenic mouse models were established. These studies have revealed that the escape of autoreactive B cells from clonal deletion or functional inactivation (clonal anergy) alone is not