Mother-to-infant transmission of hepatitis B virus infection: Significance of maternal viral load and strategies for intervention
β Scribed by Wen, Wan-Hsin; Chang, Mei-Hwei; Zhao, Lu-Lu; Ni, Yen-Hsuan; Hsu, Hong-Yuan; Wu, Jia-Feng; Chen, Pei-Jer; Chen, Ding-Shinn; Chen, Huey-Ling
- Book ID
- 120029154
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 654 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0168-8278
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The significance of IgM and IgG class antibodies to hepatitis B virus (HBV) core component (anti-HBc) was investigated in a study of maternal-fetal HBV transmission. An IgM anti-HBc response was lacking in the majority (49/53) of HBV-infected infants. This antibody thus cannot be used as an indicato
## Abstract One hundred twentyβsix motherβinfant couples were studied and 105 exposed babies were monitored for at least 12 months to define the risk of motherβtoβinfant HCV transmission. Infection occurred in 5 out of 76 infants (6.6%) born to 69 viraemic mothers and in none of 29 born to 26 nonβv