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Morin inhibits interleukin-1β-induced nitric oxide and prostaglandin E2 production in human chondrocytes

✍ Scribed by Wei-Ping Chen; Yu-Lu Wang; Jing-Li Tang; Peng-Fei Hu; Jia-Peng Bao; Li-Dong Wu

Book ID
116577037
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
491 KB
Volume
12
Category
Article
ISSN
1567-5769

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## Abstract ## Objective To investigate the effects of prostaglandin D~2~ (PGD~2~) on interleukin‐1β (IL‐1β)–induced matrix metalloproteinase 1 (MMP‐1) and MMP‐13 expression in human chondrocytes and the signaling pathways involved in these effects. ## Methods Chondrocytes were stimulated with I