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Monoclonal antibodies to human pancreatic carcinoma

โœ Scribed by SHI-ZHEN YUAN; LAURENCE J. MCINTYRE; YOUNG S. KIM

Book ID
118703675
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
441 KB
Volume
2
Category
Article
ISSN
0815-9319

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The anticancer agent neocarzinostatin (NCS) was bound covalently to human/mouse chimeric Fab fragments of the monoclonal antibody A7 to form the conjugate chA7Fab-NCS. The antitumor effect of chA7Fab-NCS was tested by measuring the inhibition of 3H-thymidine incorporation into human pancreatic carci