Neuroblastoma, along with rhabdomyosarcoma, Ewing's sarcoma, and acute lymphoblastic leukemia/lymphoma, is one of the small, round-cell tumors of childhood. All of these malignancies show a propensity to metastasize to bone marrow. Occasionally when the clinical picture is unclear and the tumor is p
Monoclonal antibodies as a model of “universal” bone marrow
✍ Scribed by K. L. Chimishkyan; A. Yu. Baryshnikov; G. Sh. Ovumyan; V. N. Kostrykina; I. A. Karpov; A. M. Buntsevich; E. G. Slavina; G. A. Udalov; Z. G. Kadagidze
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 207 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Uptake of indium-111 in bone marrow is seen in patients who have received ~llIn-labelled antibody. We report a case in which 111In uptake was not seen in the area of previous irradiation whereas fairly high uptake was noted in other bone marrow areas, l~llnlabelled monoclonal antibody, which reacts
The monoclonal antibody (MAb) 2E11 is commonly used for detection of microdisseminated epithelial cells in bone marrow of cancer patients. Surprisingly, in an earlier report 2E11 was shown to bind to mononuclear cells in bone marrow in 61% of healthy donors. In the present study we tested whether th
Metastases develop in 30% to 40% of patients with operable breast cancer. Investigators have reported on the detection of occult micrometastases in bone marrow using an antibody to epithelial membrane antigen (EMA) and have since reported prognostic significance for these antibody-detected cells. In