Metastases develop in 30% to 40% of patients with operable breast cancer. Investigators have reported on the detection of occult micrometastases in bone marrow using an antibody to epithelial membrane antigen (EMA) and have since reported prognostic significance for these antibody-detected cells. In
Immunocytochemical detection of bone marrow micrometastases in colorectal carcinoma patients, using a monoclonal antibody to villin
✍ Scribed by Roman Rouzier; Edwige Bourstyn; Frédéric Grozier; Anne Berger; Daniel Louvard; Sylvie Robine
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 521 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0196-4763
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## Abstract ## BACKGROUND The efficient detection and characterization of micrometastatic cells in the bone marrow of patients with breast carcinoma are of prognostic and therapeutic importance. The technique used must overcome the challenges that result from the small number of target cells (1 pe
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