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Monoamine oxidase B and Parkinson's disease

✍ Scribed by Steventon, G; Humfrey, C; Sturman, S; Waring, R.H; Williams, A.C

Book ID
122680985
Publisher
The Lancet
Year
1990
Tongue
English
Weight
162 KB
Volume
335
Category
Article
ISSN
0140-6736

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Monoamine oxidase B (MAO-B) is implicated in the cause of Parkinson's disease (PD) because of its role in metabolizing the neurotoxin l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, and forming H,02 during dopamine metabolism. Altered MAO-B activity has been observed in PD platelets. Polymerase chain