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Monitoring Chinese hamster ovary cell culture by the analysis of glucose and lactate metabolism

✍ Scribed by Y.-S. Tsao; A.G. Cardoso; R.G.G. Condon; M. Voloch; P. Lio; J.C. Lagos; B.G. Kearns; Z. Liu

Book ID
118194308
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
618 KB
Volume
118
Category
Article
ISSN
0168-1656

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## Abstract In an effort to develop robust Chinese Hamster Ovary host cell lines, a variety of anti‐apoptotic genes were over‐expressed, either singly or in combination, followed by screening of transfectants for improved cell growth, extended longevity, reduced caspase 3/7 activity, and enhanced m