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Molecular therapy to inhibit NFκB activation by transcription factor decoy oligonucleotides

✍ Scribed by Ryuichi Morishita; Naruya Tomita; Yasufumi Kaneda; Toshio Ogihara

Book ID
116383215
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
153 KB
Volume
4
Category
Article
ISSN
1471-4892

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## Abstract ## Background Nuclear factor‐κB (NF‐κB) transcription factor regulates the expression of genes involved in immune response and inflammation. NF‐κB activity can be efficiently inhibited by double‐stranded oligodeoxynucleotides (ODNs). In the present study, we investigated the potential