Transcription factor decoy oligodeoxynucleotides to nuclear factor-κB inhibit reverse passive Arthus reaction in rat

A decoy oligonucleotide inhibiting nucle

A decoy oligonucleotide inhibiting nuclear factor-κB binding to the IgGκB consensus site reduces cerebral injury and apoptosis in neonatal hypoxic-ischemic encephalopathy

✍ Roderic H. Fabian; J. Regino Perez-Polo; Thomas A. Kent 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract We examined the effect of treatment with intraventricular injection of a decoy oligonucleotide that binds and inhibits nuclear factor‐κB on cytokine expression, ICAM‐1 expression, neutrophil recruitment, apoptosis, and tissue injury in a model of neonatal hypoxic‐ischemic cerebral injur