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Attenuation of interleukin-8 production by inhibiting nuclear factor-κB translocation using decoy oligonucleotides∗

✍ Scribed by J.Allen D. Cooper Jr.; Jane M. Parks; Roxanna Carcelen; Summerpal S. Kahlon; Michael Sheffield; Rachel Culbreth

Book ID: 113994702
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 335 KB
Volume: 59
Category: Article
ISSN: 0006-2952
DOI: 10.1016/s0006-2952(99)00375-5

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## Abstract CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV‐1) encephalitis, but the mechanism of secretion of this chemokine is not fully unde