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Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

✍ Scribed by Takashi Tsuruo; Mikihiko Naito; Akihiro Tomida; Naoya Fujita; Tetsuo Mashima; Hiroshi Sakamoto; Naomi Haga

Book ID
108582189
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
398 KB
Volume
94
Category
Article
ISSN
1347-9032

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## Abstract Here we review an approach to the design and production of antibody/ligand pairs for use in cell targeting procedures, to achieve functional affinity far greater than avidin/biotin. Using fundamental chemical principles, we have developed antibody/ligand pairs that retain the binding sp