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Molecular profiles of progesterone receptor loss in human breast tumors

✍ Scribed by Chad J. Creighton; C. Kent Osborne; Marc J. van de Vijver; John A. Foekens; Jan G. Klijn; Hugo M. Horlings; Dimitry Nuyten; Yixin Wang; Yi Zhang; Gary C. Chamness; Susan G. Hilsenbeck; Adrian V. Lee; Rachel Schiff


Book ID
106377789
Publisher
Springer US
Year
2008
Tongue
English
Weight
823 KB
Volume
114
Category
Article
ISSN
0167-6806

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## Abstract Estrogen acts via its receptor (ER) to stimulate cell growth and differentiation in the mammary gland. ER and progesterone receptor (PR), which is regulated by estrogen via ER, have been used as prognostic markers in clinical management of breast cancer patients. Patients with ER^βˆ’^ bre