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Molecular Modeling of the Interactions of Trichosanthin with Four Substrate Analogs

✍ Scribed by Yijun Gu; Weiyan Chen; Zongxiang Xia

Book ID
110246763
Publisher
Springer
Year
2000
Tongue
English
Weight
58 KB
Volume
19
Category
Article
ISSN
1573-4943

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Crystal structures of the complexes of t
Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N-glycosidase
✍ Yi-Jun Gu; Zong-Xiang Xia πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 273 KB πŸ‘ 1 views

Four substrate analogs-nicotinamide adenine dinucleotide, adenylyl (3, 5) guanosine, guanylyl (3,5) adenosine, and adenosine 2,5-diphosphate-have been used to prepare the complexes with trichosanthin (TCS), a type I ribosome-inactivating protein that possesses the activity of N-glycosidase. The crys