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Molecular Interaction of the Antagonist N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1- (2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB 1 Cannabinoid Receptor

✍ Scribed by Shim, Joong-Youn; Welsh, William J.; Cartier, Etienne; Edwards, James L.; Howlett, Allyn C.

Book ID: 120928900
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 424 KB
Volume: 45
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm010267o

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## Abstract Two novel ligands for cerebral cannabinoid receptor (CB1), 1‐(2,4‐dichlorophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75528) and 1‐(2‐bromophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75575)