## Abstract Two novel ligands for cerebral cannabinoid receptor (CB1), 1‐(2,4‐dichlorophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75528) and 1‐(2‐bromophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75575)
Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophen-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a Potential Peripheral Cannabinoid-1 Receptor Inverse Agonist
✍ Scribed by Ming-Shiu Hung; Chun-Ping Chang; Ting-Chieh Li; Teng-Kuang Yeh; Jen-Shin Song; Yinchiu Lin; Chien-Huang Wu; Po-Chu Kuo; Prashanth K. Amancha; Ying-Chieh Wong; Wen-Chi Hsiao; Yu-Sheng Chao; Kak-Shan Shia
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 313 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1860-7179
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📜 SIMILAR VOLUMES
## Abstract The feasibility of nucleophilic displacement of bromide in the 4‐bromopyrazole ring with [^18^F]fluoride has been demonstrated by the synthesis of two radiolabeled compounds: __N__‐(piperidin‐1‐yl)‐5‐(4‐methoxyphenyl)‐1‐(2‐chlorophenyl)‐4‐[^18^F]fluoro‐1__H__‐pyrazole‐3‐carboxamide, ([^
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