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Tricyclic Pyrazoles. 4. Synthesis and Biological Evaluation of Analogues of the Robust and Selective CB2 Cannabinoid Ligand 1-(2‘,4‘-Dichlorophenyl)-6-methyl-N-piperidin-1-yl- 1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide

✍ Scribed by Murineddu, Gabriele; Lazzari, Paolo; Ruiu, Stefania; Sanna, Angela; Loriga, Giovanni; Manca, Ilaria; Falzoi, Matteo; Dessì, Christian; Curzu, Maria M.; Chelucci, Giorgio

Book ID: 115314179
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 419 KB
Volume: 49
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm060920d

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## Abstract Two novel ligands for cerebral cannabinoid receptor (CB1), 1‐(2,4‐dichlorophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75528) and 1‐(2‐bromophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75575)

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