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Molecular Genetics of RB1——The Retinoblastoma Gene

✍ Scribed by Leiderman, Yannek I.; Kiss, Szilárd; Mukai, Shizuo


Book ID
115529676
Publisher
Informa plc
Year
2007
Tongue
English
Weight
120 KB
Volume
22
Category
Article
ISSN
0882-0538

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RB1 gene mutations in retinoblastoma
✍ Dietmar R. Lohmann 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB 👁 2 views

Mutations in both alleles of the RB1 gene are causal for the development of retinoblastoma, a childhood tumor of the eye. The spectrum of somatic and germline mutations in this gene is dominated by small mutations. Data on small mutations are listed in a locus specific database available at http://w