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Molecular analysis of the retinoblastoma (RB1) gene in acute myeloid leukemia patients

✍ Scribed by Mônica Barbosa de Melo; Fernando Ferreira Costa; Sara Teresinha Olalla Saad; Irene Lorand-Metze; Silvana Bordin; Nilofer Nina Ahmad

Book ID: 114119457
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 123 KB
Volume: 22
Category: Article
ISSN: 0145-2126
DOI: 10.1016/s0145-2126(98)00047-2

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We have analyzed the 27 exons and the promoter region of the RBI gene in familial or sporadic bilateral retinoblastoma by using single-strand conformation polymorphism analysis. For improvement over previous studies, a new set of primers has been designed, which allow for amplification of the coding