Autigenic variation is OIW of the most effective strategies developed by parasites to escape inmune destruction. It requires a large wardrobe of surface coats and mechanisms to eschange one coat for an unrelated one. The molecular principles of antigenic variation are now largely known in the bacter
โฆ LIBER โฆ
Molecular genetics of antigenic variation
โ Scribed by Piet Borst
- Book ID
- 119139739
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 556 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0169-4758
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The genome of Neisseria gonorrhoeae harbours many gene loci for the production of variant pili. Strain MS 11 has two expression genes (pi/E) with promoter and complete coding sequences. The remaining genes are silent (pilS) lacking the promoter and the conservative amino terminals coding sequences o