Molecular genetics of antigenic variation

✍ Scribed by Piet Borst

• Book ID: 104298540
• Publisher: Elsevier Science
• Year: 1991
• Tongue: English
• Weight: 578 KB
• Volume: 12
• Category: Article
• ISSN: 0167-5699
• DOI: 10.1016/s0167-5699(05)80009-x

✦ Synopsis

Autigenic variation is OIW of the most effective strategies developed by parasites to escape inmune destruction. It requires a large wardrobe of surface coats and mechanisms to eschange one coat for an unrelated one. The molecular principles of antigenic variation are now largely known in the bacterial species Borrelia and Neisseria and in the protozoa of the African trypanosome group and these thee examples are discussed here by Piet Borst.