Molecular Genetic Pathology

✍ Scribed by Liang Cheng

• Publisher: Humana Press
• Year: 2008
• Tongue: English
• Leaves: 784
• Edition: 1
• Category: Library

✦ Synopsis

Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Part I examines the clinical areas of molecular biology, genomics, pharmacogenomics and proteomics, while Part II covers the molecular areas of medical genetics, microbiology, hematology, transfusion medicine, oncology and forensic pathology. The volume provides a unique reference for the practicing pathologist and medical geneticist as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

✦ Table of Contents

Front
......Page 1
Preface
......Page 5
Contents......Page 6
Contributors......Page 8
Part I
General Sections......Page 12
1
Principles of Clinical Molecular Biology......Page 13
2
Principles of Clinical Cytogenetics......Page 43
3
Diagnostic Methodology and Technology......Page 74
4
Tissue Microarrays and Biomarker Validation......Page 141
5
Laser Capture Microdissection......Page 149
6
Clinical Flow Cytometry......Page 163
7
Conceptual Evolution in Cancer Biology......Page 192
8
Clinical Genomics in Oncology......Page 216
9
Clinical Proteomics......Page 237
10
Clinical Pharmacogenomics......Page 246
11Clonality Analysis in Modern Oncologyand Surgical Pathology......Page 265
12
Fluorescence In Situ Hybridization (FISH)
and Conventional Cytogenetics for Hematology
and Oncology Diagnosis......Page 306
13
Instrumentation......Page 368
14
Genetic Inheritance and Population Genetics......Page 396
15
Genetic Counseling......Page 407
Part II
Disease-Based Sections......Page 416
16
Molecular Medical Genetics......Page 417
17
Prenatal Diagnosis......Page 441
18
Familial Cancer Syndromes......Page 449
19
Molecular Testing for Solid Tumors......Page 467
20
Molecular Pathology of the Central Nervous System......Page 496
21
Molecular Virology......Page 532
22
Molecular Bacteriology, Mycology,
and Parasitology......Page 580
23
Molecular Testing for Coagulopathies......Page 622
24
Molecular Hemoglobinopathies......Page 636
25
Molecular Diagnostics
of Lymphoid Malignancies......Page 654
26
Molecular Diagnostics of Myeloid Leukemias......Page 674
27
The HLA System and Transfusion Medicine......Page 688
28
Molecular Forensic Pathology......Page 702
29
Gene Therapy......Page 716
30
Ethical and Legal Issues in Molecular Testing......Page 729
31
Quality Assurance and Laboratory Inspection......Page 735
Index......Page 764