Molecular Genetic Pathology

✍ Scribed by Shaobo Zhang MD, Darrell D. Davidson MD, PhD, David Y. Zhang MD, PhD, MPH (auth.), Liang Cheng MD, David Y. Zhang MD, PhD, MPH (eds.)

• Publisher: Humana Press
• Year: 2008
• Tongue: English
• Leaves: 784
• Category: Library

✦ Synopsis

Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Part I examines the clinical areas of molecular biology, genomics, pharmacogenomics and proteomics, while Part II covers the molecular areas of medical genetics, microbiology, hematology, transfusion medicine, oncology and forensic pathology. The volume provides a unique reference for the practicing pathologist and medical geneticist as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

✦ Table of Contents

Front Matter....Pages i-xii
Front Matter....Pages 1-1
Principles of Clinical Molecular Biology....Pages 3-32
Principles of Clinical Cytogenetics....Pages 33-63
Diagnostic Methodology and Technology....Pages 65-131
Tissue Microarrays and Biomarker Validation....Pages 133-140
Laser Capture Microdissection....Pages 141-154
Clinical Flow Cytometry....Pages 155-183
Conceptual Evolution in Cancer Biology....Pages 185-208
Clinical Genomics in Oncology....Pages 209-229
Clinical Proteomics....Pages 231-239
Clinical Pharmacogenomics....Pages 241-259
Clonality Analysis in Modern Oncology and Surgical Pathology....Pages 261-301
Fluorescence In Situ Hybridization (FISH) and Conventional Cytogenetics for Hematology and Oncology Diagnosis....Pages 303-364
Instrumentation....Pages 365-392
Genetic Inheritance and Population Genetics....Pages 393-403
Genetic Counseling....Pages 405-413
Front Matter....Pages 415-415
Molecular Medical Genetics....Pages 417-440
Prenatal Diagnosis....Pages 441-448
Familial Cancer Syndromes....Pages 449-466
Molecular Testing for Solid Tumors....Pages 467-495
Molecular Pathology of the Central Nervous System....Pages 497-532
Front Matter....Pages 415-415
Molecular Virology....Pages 533-580
Molecular Bacteriology, Mycology, and Parasitology....Pages 581-622
Molecular Testing for Coagulopathies....Pages 623-636
Molecular Hemoglobinopathies....Pages 637-654
Molecular Diagnostics of Lymphoid Malignancies....Pages 655-674
Molecular Diagnostics of Myeloid Leukemias....Pages 675-688
The HLA System and Transfusion Medicine....Pages 689-702
Molecular Forensic Pathology....Pages 703-716
Gene Therapy....Pages 717-729
Ethical and Legal Issues in Molecular Testing....Pages 731-736
Quality Assurance and Laboratory Inspection....Pages 737-750
Back Matter....Pages 751-787

✦ Subjects

Pathology; Human Genetics; Molecular Medicine