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Molecular Features of Neonicotinoid Pharmacophore Variants Interacting with the Insect Nicotinic Receptor

โœ Scribed by Ohno, Ikuya; Tomizawa, Motohiro; Durkin, Kathleen A.; Naruse, Yuji; Casida, John E.; Kagabu, Shinzo


Book ID
111973102
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
229 KB
Volume
22
Category
Article
ISSN
0893-228X

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Substituted-phenoxycarbonylimino neonicotinoid ligands with an electron-donating group showed significantly higher affinity to the insect nicotinic receptor relative to that of the analogue with an electron-withdrawing substituent, thereby establishing in silico binding site interaction model featur