Translocation t(11;21)(q24;q11.2) is a rare but recurrent chromosomal abnormality associated with myelodysplastic syndrome (MDS) that until now has not been characterized at the molecular level. We report here results of a molecular cytogenetic analysis of this translocation in a patient with refrac
Molecular cytogenetic analysis discloses complex genetic imbalance in a t(11;21) myelodysplastic syndrome
β Scribed by Simonetta Kerim; Giovanna Rege-Cambrin; Angelo Guerrasio; Claudia Rosso; Herman Van Den Berghe
- Book ID
- 119104632
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 391 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Fluorescence in situ hybridization (FISH) using chromosome-specific plasmid libraries and chromosome region-specific DNA markers allowed the characterization of a t( 1022; I I ) (p I I .2;q I2;q24) in a Ewing's sarcoma (ES). This study illustrates the usefulness of molecular cytogenetic analysis of
## Background: Data on genome-wide surveys for chromosome aberrations in primary cutaneous t-cell lymphoma (ctcl) are limited. ## Objective: To investigate genetic aberrations in ctcl. ## Methods: We analysed 18 cases of sΓ©zary syndrome (ss) and 16 cases of mycosis fungoides (mf) by comparative