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Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues

✍ Scribed by Peter Krajci; Rigmor Solberg; Mårten Sandberg; Ole Øyen; Tore Jahnsen; Per Brandtzaeg

Book ID
115762654
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
752 KB
Volume
158
Category
Article
ISSN
0006-291X

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The human transmembrane secretory component (SC) mediates glandular translocation of polymeric IgA and IgM into exocrine secretions. A 2898-bp cDNA clone, encoding the entire sequence of the human transmembrane SC, was isolated from a colonic adenocarcinoma cell line cDNA library. The deduced amino-