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Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor)

✍ Scribed by Peter Krajči; Dag Kvale; Kjetil Taskén; Per Brandtzaeg


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
754 KB
Volume
22
Category
Article
ISSN
0014-2980

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The human transmembrane secretory component (SC) mediates glandular translocation of polymeric IgA and IgM into exocrine secretions. A 2898-bp cDNA clone, encoding the entire sequence of the human transmembrane SC, was isolated from a colonic adenocarcinoma cell line cDNA library. The deduced amino-