Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases
β Scribed by Takamune Takahashi; Takuji Shirasaw
- Book ID
- 115930271
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 919 KB
- Volume
- 342
- Category
- Article
- ISSN
- 0014-5793
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A member of a new class of protein tyrosine kinases, JAK1, has been mapped to lp31.3 by in situ hybridization and Southern blot analysis of a panel of mouse-human hybrid cell lines. A murine protein tyrosine kinase, related to, but distinct, from JAK1, was mapped by in situ hybridization to human Ch
Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs