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Localization of genes for two members of the JAK family of protein tyrosine kinases to murine Chromosomes 4 and 19

✍ Scribed by N. M. Gough; S. Rakar; A. Harpur; A. F. Wilks

Publisher: Springer-Verlag
Year: 1995
Tongue: English
Weight: 158 KB
Volume: 6
Category: Article
ISSN: 0938-8990
DOI: 10.1007/bf00352409

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✦ Synopsis

Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs lp31-3 (JAK1) and 9p24 (JAK2). The location of Jak-2 in the mouse genome extends the region of homology between mouse Chr 19 and human Chr 9.

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