## Abstract Human immunodeficiency virus 2 (HIV‐2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV‐2 as a model
Molecular characterization of the CCR 5 gene in seronegative individuals exposed to human immunodeficiency virus (HIV)
✍ Scribed by M.T. Rugeles; F. Solano; F.J. Dı́az; V.I. Bedoya; P.J. Patiño
- Book ID
- 117769484
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 266 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1386-6532
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The 32 nucleotide deletion in the CCR-5 chemokine receptor gene referred to as ⌬ccr-5 has been shown to confer resistance to HIV-1. Using PCR, 1,105 human subjects and 33 common chimpanzees were genotyped attributing them to one of the three possible genotypes: wild-type homozygote (w/w); ⌬ccr-5 hom