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Stromal cell-derived factor 1 (SDF1) genetic polymorphism in a sample of healthy individuals, seronegative individuals exposed to human immunodeficiency virus type 1 (HIV-1) and patients infected with HIV-1 from the Brazilian population

✍ Scribed by E. M. V. Reiche; M. A. E. Watanabe; A. M. Bonametti; H. K. Morimoto; A. A. Morimoto; S. L. Wiechmann; T. Matsuo; H. C. Miranda; F. V. Reiche; K. B. Oliveira

Book ID: 114831334
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 95 KB
Volume: 33
Category: Article
ISSN: 1744-3121
DOI: 10.1111/j.1744-313x.2006.00583.x

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## Abstract The Th1–Th2 balance plays a pivotal role in determining the outcome of an immune response to an infectious organism. It is proposed that during HIV infection, disease progression is characterized by a loss of Th1 activity, a shift to a more ‘allergic’ Th2‐type response and hence loss of