Molecular characterization of parathyroid tumors from two patients with hereditary colorectal cancer syndromes
✍ Scribed by Adam Andreasson, Luqman Sulaiman, Sónia do Vale, João Martin Martins, Florbela Ferreira, Gabriel Miltenberger-Miltenyi, Lucas Batista, Felix Haglund, Erik Björck, Inga-Lena Nilsson, Anders Höög, Catharina Larsson, C. Christofer Juhlin
- Book ID
- 111962076
- Publisher
- Springer Netherlands
- Year
- 2012
- Tongue
- English
- Weight
- 594 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1389-9600
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## Abstract We report the cytogenetic study of 9 colorectal tumors arising in patients with hereditary non‐polyposis colorectal cancer (HNPCC). According to the cytogenetic classification of colorectal tumors previously proposed by us, 2 cases were of the trisomic type, 2 were of the monosomic type
## BACKGROUND. The hereditary nonpolyposis colorectal carcinoma (HNPCC) syndrome is an autosomal dominant genetic disorder caused by the inheritance of a mutation in one of a family of genes encoding DNA mismatch repair (MMR) proteins. HNPCC manifests as genetic instability in linked tumors. Clini