Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer
β Scribed by Halvarsson, Britta; Lindblom, Annika; Johansson, Leif; Lagerstedt, Kristina; Nilbert, Mef
- Book ID
- 109888224
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 432 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0893-3952
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## Abstract Germline mutations in DNA mismatch repair genes underlie one of the most common hereditary cancer predisposition syndromes known in humans, hereditary nonpolyposis colorectal cancer (HNPCC). Defects of the DNA mismatch repair system are also prevalent in sporadic colorectal cancers. The
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