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Molecular characterization of a rare MLL–AF4 (MLL–AFF1) fusion rearrangement in infant leukemia

✍ Scribed by Susana Bizarro; Nuno Cerveira; Cecília Correia; Susana Lisboa; Ana Peixoto; Lucília Norton; Manuel R. Teixeira

Book ID
113513178
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
390 KB
Volume
178
Category
Article
ISSN
0165-4608

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Insertion of MLL sequences into chromosome band 5q31 results in an MLL-AF5Q31 fusion and is a rare but recurrent abnormality associated with infant leukemia
✍ Ramona Deveney; David S. Chervinsky; Sheila N. Jani-Sait; Mauro Grossi; Peter D. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB

## Abstract __MLL__ gene rearrangements leading to production of MLL fusion proteins are commonly detected in infant leukemia patients; the most common __MLL__ fusion associated with infant leukemia is the __MLL‐AF4__ fusion. A single case of chromosomal rearrangement leading to production of an __